Our technology
Combining a bioreactor and a centrifuge
Limula's core technology combines the functionalities of a bioreactor and a centrifuge, enabling both cell incubation and processing in a single vessel. This ‘one-pot’ approach minimises process footprint and complexity by eliminating the need for cell transfers between multiple devices. As a result, it reduces cell stress and loss, improving the overall quality of the product.
Incubation
Cell expansion across scales
Horizontal positioning allows for incubation functionalities. This orientation unlocks a large dynamic volume range, from as little as 2 mL up to 400 mL, enabling stage-appropriate scale down during process development and seamless scale up for clinical production.
Scalable volumes
From 2 mL to 400 mL, supporting both early-stage studies and large-scale runs
Exceptional expansion
Superior cell growth compared to commonly used bioreactors
Unmatched versatility
Adaptable to diverse workflows, including CAR-T, HSCs, NK, TILs, and more to follow
Processing
Fast, gentle, precise volume management
Vertical orientation enables centrifugation and related operations. This positioning supports gentle yet efficient cell handling, ensuring product quality while streamlining the workflow.
High cell viability
Gentle, low-shear centrifugation maintains cell health and maximises recovery
Low dead volumes
Precise volume control reduces product loss and ensures consistent batch yield
Flexible processing
Fast processing that can be implemented seamlessly at any stage of the workflow